陈超,伟德BETVLCTOR1946研究员,博士生导师, 硕士生导师, 副院长。国自然优秀青年基金获得者;入选湖南省创新领军人才、湖湘高层次人才聚集工程创新团队。湖南省青年骨干教师培养对象。中国遗传学会青年委员会委员、中华医学会医学遗传学分会生物信息学组副组长、湖南省生物信息学会副理事长、湖南省遗传学会常务理事、湖南省神经科学学会理事等职务。
陈超研究员于2011获复旦大学理学博士学位,在美国芝加哥大学和伊利诺利大学从事5年的精神遗传与生物信息学研究。研究着重于:1、基于人脑组织的基因表达调控及在神经精神疾病中的作用,2、多组学相关的生物信息学研究,3、人脑类器官模型开发及在神经精神疾病中的应用。主要工作发表在Science、Science Translational Medicine(2篇)、Molecular Psychiatry(7篇)、Bioinformatics等杂志,累计他引超3000次。研究工作先后获得美国人类遗传学会Charles J. Epstein 奖(2017,2018),世界精神遗传学会Hugh Gurling奖(2016,2020)。
担任Genes期刊客座主编,Frontier in Aging Neuroscience、JPBS等期刊编委,Genome Biology、Molecular Psychiatry、Journal of Neuroscience等期刊特邀审稿人。主持国自然优秀青年基金、面上项目等10余项基金,作为研究骨干参与科技部重大研发专项1项,累计进账经费超1000万元。出版专著3本,获批专利2项。
课题组拥有教授2人,讲师/博士后4人。学术自由,科研气氛浓厚。团队年龄结构合理,朝气蓬勃。国际合作广泛,课题组大力支持学生出国参加国际知名学术会议做报告,并且多人获奖。已毕业同学远赴哈佛大学、MIT、芝加哥大学、UCSD等学校继续深造,数人已取得教职。目前招收生物医学信息学和遗传学专业的博士生和硕士生,期待具备好奇心、恒心、耐心、细心的优秀学子报考。
课题组介绍:
https://www.bilibili.com/video/BV1PT4y1Q7t1?share_source=copy_web
教师个人主页:
https://faculty.csu.edu.cn/ChenChao/zh_CN/index.htm
博士后招聘信息:/copy_2_nr.jsp?urltype=news.NewsContentUrl&wbtreeid=1827&wbnewsid=2723
科研成果新闻报道:
https://news.bioon.com/article/6732267.html
https://www.cas.cn/kj/201812/t20181221_4674513.shtml
https://news.csu.edu.cn/info/1004/151182.htm
近五年代表性论文:
1. Chaodong Ding, Chunling Zhang, Richard Kopp, Liz Kuney, Qingtuan Meng, Le Wang, Yan Xia, Yi Jiang, Rujia Dai, Shishi Min, Wei-Dong Yao, Ma-Li Wong, Hongyu Ruan*, Chunyu Liu*, Chao Chen*. Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia. Molecular Psychiatry. 26, 3444–3460 (2021)
2. Qingtuan Meng*, Le Wang, Rujia Dai, Jiawen Wang, Zongyao Ren, Sihan Liu, Yan Xia, Yi Jiang, Fangyuan Duan, Kangli Wang, Chunyu Liu*, Chao Chen*. Integrative analyses prioritize GNL3 as a risk gene for bipolar disorder. Molecular Psychiatry. 25, 2672–2684 (2020)
3. Yi Jiang, Gina Giase, Kay Grennan, Annie W. Shieh, Yan Xia, Lide Han, Quan Wang, Qiang Wei, Rui Chen, Sihan Liu, Kevin P. White, Chao Chen*, Bingshan Li,*, Chunyu Liu*, DRAMS: A Tool to Detect and Re-Align Mixed-up Samples for Integrative Studies of Multi-omics Data. PLoS Computational Biology, 2020 Apr 13;16(4):e1007522
4. Yan Xia, Rujia Dai, Kangli Wang, Chuan Jiao, Yuchen Xu, Honglei Li, Xi Jing, Yu Chen, Richard Kopp, Gina Giase, Chunling Zhang, Yi Jiang, Chao Chen*, Chunyu Liu*. Sex-differential DNA methylation and associated regulation networks in human brain implicated in the sex-biased risks of psychiatric disorder. Molecular Psychiatry, 26, 835–848 (2021)
5. Qingtuan Meng, Kangli Wang, Tonya Brunetti, Yan Xia, Chuan Jiao, Dominic Fitzgerald, Amber Thomas, Lindsey Jay, Heather Eckart, Kay Grennan, Kevin P. White, The PsychENCODE Consortium, Chao Chen*, Chunyu Liu*, The DGCR5 long noncoding RNA may regulate expression of several schizophrenia-related genes. Science Translational Medicine, 2018;10(472):eaat6912. doi:10.1126/scitranslmed.aat6912
6. Chao Chen*, Qingtuan Meng, Yan Xia, Chaodong Ding, Lijun Cheng, Preethi Gunaratne, Richard A. Gibbs, Shishi Min, Rujia Dai, Le Wang, Cristian Coarfa, Jeffrey G. Reid, Chunling Zhang, Chuan Jiao, Yi Jiang, Gina Giase, Amber Thomas, Dominic Fitzgerald, Tonya Brunetti, Annie Shieh, Cuihua Xia, Yongjun Wang, Yunpeng Wang, Judith A. Badner, Elliot S. Gershon, Kevin P White, Chunyu Liu*. The transcription factor POU3F2 regulates a gene coexpression network in brain tissue from patients with psychiatric disorders. Science Translational Medicine, 10(472):eaat8178 (2018).
7. Le Wang, Yan Xia, Yu Chen, Rujia Dai, Wenying Qiu, Chao Chen*. Brain Banks Spur New Frontiers in Neuropsychiatric Research and Strategies for Analysis and Validation. Genomics, Proteomics & Bioinformatics, August 2019 17(4): 402-414
8. Chuan Jiao, Lingling Huang, Rujia Dai, Yu Wei, Cuihua Xia, Jiacheng Dai, Yan Xia, Shunan Zhao, Liu Yi, Qingtuan Meng, Kangli Wang, Chunyu Liu*, Chao Chen*. BrainEXP: a database featuring with spatiotemporal expression variations and co-expression organizations in human brains. Bioinformatics, 2019 Jan 1;35(1):172-174.
更多论文:https://scholar.google.com/citations?hl=en&user=IOapW6oAAAAJ